June,  2011

 

CURRICULUM VITAE

 

 

 

NAME:   Bum-Chae Choi, M.D., Ph.D.

 

ADDRESS:

Department of Obstetrics and Gynecology

Center for Recurrent Miscarriage and Infertility

Creation and Love women's Hospital

13-21, Gwangchun-dong, Seo-ku, Gwangju City, 502-210,

Korea.

E-mail; cbcmd@unitel.co.kr

 

PERSONAL INFORMATION:

Date of Birth: 03/16/1960

Place of Birth: Gwangju City, Korea

Wife: Hyun-Sook Roh

Sons: Sung-Woo Choi,

         Jin-Woo Choi

 

EDUCATION:

1985 M.D. School of Medicine, Chosun University, Gwangju-City

2000 M.S. School of Medicine, Kunkok University, Seoul

2007 Ph.D. Ggraduate school of Pharmacy,

School of Medicine, Chosun University, Gwangju-City

 

POSTDOCTORAL TRAINING:

Millitary service: 1985~1988

Intership and Residency:

1988~1989 Internship in Samsung Cheil Hospital

1989~1993 Residency course in Obstetrics and Gynecology,

                   School of Medicine, Kunkok University, Seoul

Clinical and Research fellowships:

1993~1995 Fellow in Reproductive Medicine and Infertility,

                   Samsung Cheil Hospital, School of Medicine, Sungkyunkwan University, Seoul

1995~1997 Research Fellow in Reproductive Immunology,

                   Fearing Research laboratory, Brigham and Women's Hospital

                   Harvard Medical School.

 

 

LICENCES AND CERTIFICATION:

1985 Diplomat, Korean Board of Medical Examiners,

Certification No. 28764

1993 Diplomat, Korean Board of Obsterics and Gynecology, 1997 Diplomat, Division of Reproductive Immunology,

Brigham and Women's Hospital, Harvard medical School

 

ACADEMIC AND HOSPITAL APPOINTMENT:

1997~1998 Clinical Assistant Professor in Obstetrics and Gynecology,

                   School of Medicine, Sungkyunkwan University

1998~2000 Assistant Professor in Obstetrics and Gynecology,

                   School of Medicine, Sungkyunkwan University

2000~ Director, Center for Recurrent Miscarriage and Infertility,

           Deparment of Obstetrics and Gynecology,

           Creation and Love Women's Hospital, Gwangju City

2001~ Clinical Associate Professor in Obstetrics and Gynecology,

            School of Medicine Sungkyunkwan University

2001; Modulater in ASRM meeting

2002; Reviewer in ESHRE meeting

2002~2004; Visiting Lecturer Assistant Professor, College of Engineering,

         Chosun University

2003~ Member of International Cooperation & Communication in

Korean Society for Assisted Reproduction

2005~ Member of Advisory Committee of AOCOG 2005

2005~ Chief of Academic Committee of KOSAR 2005

2006~ Clinical Professor in Obstetrics and Gynecology,

         School of Medicine Sungkyunkwan University

School of Medicine, Chosun University, Gwangju-City

School of Medicine, Kunkok University, Seoul

2008~ Visiting Lecturer Assistant Professor, College of Bio-engineering,

         Chunnam University

 

 

AWARDS:

 

1997 Prize Paper Award - 53th American Society of Reproductive

         Medicine(ASRM)

1999 Prize Paper Award - 55th American Society of Reproductive

         Medicine(ASRM)

1999 Prize Paper Award - Seminar in Samsung Cheil Hospital

2002 Prize Paper Award - Korean Society of Fertility and Sterility

2006 KHUPO 6th Annual International Proteomics Conference

(Poster Award)

2008 Prize Paper Award - Korean Society for Assisted Reproductive Technology

2010 Prize Paper Award – FertiLink2010 Key Issues Facing Fertility in Asia

 International Ovarian Conference 2010. KYOTO, Japan.

2010 Prize Paper Award - Korean Society for Assisted Reproductive Technology

 

 

 

MEMBERSHIPS:

 

1989 Member, Korean Obstetrics and gynecology

1993 Member, Korean Fertility and Sterility

1994 Member, Korean Obstetrics and gynecology

Member, American Society of Fertility and Sterility

Member, European Society of Human Reproduction Education

1995 Member, Japanes Society of Implantation

1997 Member, Korean Society of Endoscopic Sugery

Member, Korean Society of Menopause

2001 Member, Asia-Pacific Society of Menopause

2003 Member, Korean Society for Assisted Reproduction

 

 

MAJOR RESEARCH INTERESTS:

1. Immunologic mechanims of recurrent miscarraige

2. ART (Assisted reproductive Technology)

    IVF-ET (In Vitro Fertilization)

3. PCOD (polycystic ovarian disease) 

 

BIBLIOGRAPHY

 

Books: Human Genetics(2001)

Primary Care of Women Mosby(2002)

 

 

 

 

Chapters:

 

BC Choi, K Polgar, X Ling, JA Hill. Progesterone inhibits In Vitro Embryotoxic Th1 cytokine production to trophoblast in women with recurrent pregnancy loss. Progesterone: A natural, life-supporting hormone. Editors: D. de Ziegler and C. Bulletti. Hum Reprod vol. 15, (suppl), pp.46-59, 2000

 

JA Hill, BC Choi: Immunodystrophism: Evidence for a Novel Alloimmune Hypothesis for Recurrent Pregnancy Loss Involving Th1-Type Immunity to Trophoblast. In: Adashi EY, Silver RM and Hill JA, editors: Seminar in Reproductive Medicine, New York Stuttgart, 2000, Thieme Co..

 

JA Hill , BC Choi: Recurrent Spontaneous Early pregnancy Loss. In Berek JS, Adashi and Hillard PA, editors: Novak's Gynecology: Self-Assessment and Review, 2002 in press, Williams and Wilkins Co.

 

BC Choi: Recurrent Miscarriage: Pregnancy Sucess & Failure. Life Issue 8: 22-23.

 

 

 

  

 ORIGINAL REPORTS:

 

1. SN Kim, BC Choi, DH Kim. A Case of Clear Cell Carcinoma of the Ovary Associated with Endometriosis and Uterine Myoma. Kor J Obstet Gynecol. 1991;34(3);450-454.

 

2. BC Choi, SN Kim, IJ Cho, DH Kim, Two Cases of Ovarian Pregnancy. Kor J Obstet Gynecol 1991;36(3);409-414.

 

3. BC Choi, SN Kim, IJ Cho, DH Kim. The Estimation of Gestational Age by Ultrasonographic Measurement of the Fetal Limb Bones and Biparietal Diameter. Kor J Obstet Gynecol 1993;36(7);2610-2616.

 

4. ES Kim, BC Choi, JH Hwang et al., Clinical Significance of Histocompatibility in Unexplained Recurrent Habitual Abortion. Kor J Obstet Gynecol 1995;38(7);1147-1157.

 

5. KJ Yoo, BC Choi, WW Lee, SN Kim et. al., Clinical Significance of Urinary Epidermal Growth Factor in Gynecologic Tumors. Kor J Obstet Gynecol 1997;40(4);872-878.

 

6. BC Choi, Joseph A Hill. The effects of progesterone on cll mediated immunity to trophoblast in women with recurrent pregnancy loss. Kor Fertil Steril 1997;24(3);399-405.

 

7. BC Choi, KJ Yoo, JP Lee, EC Paik et. al., Serum Tumor Necrosis Factor-α levels in Women with Recurrent Pregnancy Loss. Kor J Obstet Gynecol 1997;41(1); 176-180.

 

8. BC Choi, Joseph A Hill. TGF-β1 secretion in response to trophoblast antigen and progesterone in women with unexplained recurrent spontaneous abortion. Kor J Obstet Gynecol 1997;41(3); 725-729.

 

9. JH Jun, CK Lim, JW Kim, HK Byun, BC Choi et al.,. Analysis of Factors Affecting Fertilization and Pregnancy rate in Intracytoplasmic Sperm Injection Using Ejaculated Sperm. Kor J Obstet Gynecol 1997;41(4);1001-1007.

 

10. KJ Yoo, JH Song, IO Song, BC Choi et al., Comparison of The Clinical Efficacy of Short Flare-Up Protocols between Follicle Stimulating Hormone(FSH) and Combination with Human Menopausal Gonadotropin(HMG) Used in In-Vitro Fertilization in The Patient With Tubal Factor Infertility. Kor J Obstet Gynecol 1998;41(5):13361345.

 

11. IO Song, JH Song, Sj Hong, KJ Yoo, BC Choi, et. al., Efficancy and Pregnancy rates of Administration of Prophylactic Albumin or Elective Cryopreservation of All Embryos for Prevention of Ovarian Hyperstimualtion Syndrome in IVF-ET. Kor J Obstet Gynecol 1998;41(6):1564-1569.

 

12. BC Choi, Joseph A. Hill. When do losses of maternal lymphocytes response to trophoblast antigen or alloantigen occur in women with a history of recurrent miscarriage? Kor Fertil Steril; 1998;25(2);115-122

 

13. JE Lim, KJ Yoo, BC Choi et al., Comparative Study of Perinatal Outcome and the Incidence of Congenital Anomalies of Babies Born after Intracytoplasmic Sperm injection(ICSI) and Conventional In-vitro fertilization(IVF). Kor Fertil Steril 1998;25(3):1-7.

 

14. JH Song, KJ Yoo, IO Song, BC Choi et al., Prediction and Clinical Evaluation of Ovarian Hyperstimulation Syndrome. Kor J Obstet Gynecol 1998;41(11):2849-2852.

 

15. BC Choi, HK Byun, JA Lee, JW Kim, HJ Kim et. al., Th1 cytokine(IFN-γ) secretion pattern of peripheral blood mononuclear ceels response to trophoblast antigen in women with unexplained recurrent spontaneous abortion and normal fertile controls. Kor J Obstet Gynecol 1998;41(12):3063-3068.

 

16. KJ Yoo, JH Song, IO Song, BC Choi et al., Reproductive Outcome of Women with Recurrent Abortion or Infertiltiy Following Treatment by Operative Hysteroscopy for an Intrauterine Septum. Kor J Obstet Gynecol 1998;41(12):3034-3039.

 

17. BC Choi, YY Cho, JA Hill. Progesterone suppresses the proliferative response of maternal lymphocytes to recall antigens and alloantigen in women with a history of recurrent spontaneous abortion during pregnancy. The International J of Chosun University 1998;1(3);367-371.

 

18. BC Choi , JA Hill. Th1/Th2 cytokine reaction to IL-12 and IL-15 secretion in response to trophoblat in unexpalined recurrent aborters and fertile controls. The International J of Chosun University 1998;1(3)373-378.

 

19. KJ Yoo, JH Song, IO Song, BC Choi et. al., The Clinical Impact of Endometriosis on the Outcome IVF-ET in Infertility Patients. Kor J Obstet Gynecol 1999; 42(4); 807-813.

 

20. MR Kim, IO Song, HJ Yeon, BC Choi et. al., Gonadotropin Releasing Hormone Agonist Stimulation Test(GAST) for Prediction of Ovarian Response in Controlled Ovarian Stimulation(COH). Kor J Fertil Steril 1999; 26(2): 163-170.

 

21. IO Song, SR Hong, SJ Hong, BC Choi et. al., Expression of Nitric Oxide Synthase in the Endometrium During the Menstrual Cycle. Kor J Obstet Gynecol 1999; 42(6): 1272-1277.

 

22. BC Choi, K Polgar, X Ling, JA Hill. Progesterone inhibits In Vitro Embryotoxic Th1 cytokine production to trophoblast in women with recurrent pregnancy loss. Hum Reprod vol. 15, (suppl), pp.46-59, 2000 ~ Prize Paper Award in ASRM on 1997

 

23. CK Lim, MH Han, JH Jun, KJ Song, JW Kim, BC Choi, et al.,. Clinical application of preimplantation genetic diagnosis(PGD) using fluorescence in- situ hybridization to balanced reciprocal or Robertsonian translocation carriers in human IVF-ET program. Kor Obstet Gynecol 2000; 43(7): 1147-1153.

 

24. BC Choi, SC Kim, HS Lee, KH Bae, DJ Anderson, JA Hill, KC Kimm. Expression of telomerase activity in chorionic villi from missed abortion and undergoing surgical termination of first trimester pregnancy. (submitted) ~ Prize Paper Award in ASRM on 1999

 

25. KJ Yoo, KM Yang, BC Choi et. al., The Clinical Efficay of Medical Treatment and/or laparoscopic Surgery for the Improvement of Pregnancy Rate after IVF-ET in the Infertile patients with Endometriosis. Kor J Obstet Gynecol 2000; 43(3): 400-405.

 

26. JW Kim, HK Byun, HW Youm, JH Jun, BC Choi et. al., Analysis of Factors Affecting Survival and Pregnancy rate in frozen-Thawed embryo Transfer. Kor J Fertil Steril 2000; 27(1): 59-65.

 

27. CH Kim, BC Choi et. al., A Clinical Study on the Incompetent Internal Os of Cervix. Kor J Perinat 2000; 11(2): 197-203.

 

28. KH Kim, BC Choi et. al., The Incidence of fetal chromosomal abnormalities in recurrent miscarriage couples with balanced translocation. Kor J Obstet Gynecol 2000; 43(7): 1198-1193.

 

29. JA Lee, BC Choi, JW, Kim, JA Hiil et. al., Implication for early implantation failure in women with hydrosalpinx: hydrosalpingeal fluid inhibits trophoblast cell proliferation in vitro culture system. Kor J Obstet Gynecol 2000; 43(8): 1344-1348.

 

30. KM Yang, KJ Yoo, BC Choi et. al., Clinical efficacy of long-term Down regulation for Intrauterine Insemiantion or In vitro fertilization in Patients with Endometriosis or Adenomyosis. Kor J Obstet Gynecol 2000; 43(10): 1775-1779.

 

31. HC Kim, BC Choi et. al., Simultaneous bilateral tubal pregnancies following in-vitro fertilization and embryo transfer. Kor J Obstet Gynecol 2000; 43(4): 751-754.

 

32. DJ Lee, KJ Yoo, BC Choi et. al., Chromosomal Analysis of Abortuses in recurrent Spontaneous Aborters with Serum Anticardiolipin Antibodies. Kor J Obstet Gynecol 2000; 43(5): 871-876.

 

33. KJ Yoo, BI Yoon, BC Choi, SN Kim. The role of human leukocyte antigen(HLA)-G gene in chorionic villi during the early stage of pregnancy. Kor J Obstet Gynecol 2001; 44(1); 57-64.

 

34. JA Hill, Choi BC. Maternal immunological aspects of pregnancy success and failure. J Reprod Fertil 2000(Supp55), pp. 91-97

35. JS Cho, YS Kang, IG Moon, BC Choi et. al., Telomerase Activity and Expression of MIB-1 and bcl-2 in Human Chorionic Villi from Early and term Normal pregnancy. The Kor J Pathology 2000; 34(11): 927~33.

 

36. JA Hill, BC Choi. Immunodystrophism: Evidence for a novel Alloimmune Hypothesis for Recurrent pregnancy loss Involving Th1-Type Immunity to Trophoblast. SEMINAR IN REPRODUCTIVE MEDICINE 2000; 8(4):401-405.

 

37. JA Lee, JW Kim, BC Choi, KM Yang, YY Cho, SR Hong. Immunolocalization of the Apoptotic Inhibiting Protein(bcl-2) in Early Normal pregnancy and Abortion. The Kor J Pathology 2001; 35(1): 48~52.

 

38. HJ Kang, SC Kim, CW Kim, CW Kim, KC Kimm, BC Choi, et al., Short-term phytohaemagglutinin-activated mononuclear cells induce endothelial progenitor cells from cord blood CD34+ cells. British J Hematol 2001; 113: 962-969.

 

39. Choi, B. C., Kim, J. W., Lee, J., Yoo, K. J., Byun, H. K., Hwang, C. S., Moon, I. K., Kim, S. N., and Baek, K.-H. (2001). The effect of exocelomic fluid in the first trimester pregnancy on trophoblast cell proliferation in vitro. Kor. J. Obs. Gyn. 44: 1678-1684.

 

40. JA Hill, BC Choi. Early pregnancy Disorders: SPONTANEOUS and Recurrent pregnancy Loss. 2002; Primary Care of Women, Mosby 2002

 

41. KM Yang, HK Ahn, KJ Yoo, BC Choi, et al., Chromosomal analysis of aborted conceptuses among anembryonic pregnancy and embryonic pregnancy: Do Chromosomal abnormalities related to anembryonic pregnancy? Kor J Obstet Gynecol 2002; 45(4); 673-677.

 

42. KH Baek, BC Choi, JH Lee, JW Kim et al., The comparision of gene expression at the feto-maternal interface between normal and recurrent spontaneous abortion patients. Reprod, Fertil and Develop 2002; 14: 235-240.

 

44. JA Hill, BC Choi: Recurrent Spontaneous Early pregnancy Loss. In Berek JS, Adashi and Hillard PA, editors: Novak's Gynecology: Self-Assessment and Review, 2002, Williams and Wilkins Co.

 

45. CH Song, KY So, SC Pak, CH Jang, BC Choi, G Flouret, R Mehendale. Comparision of oxytocin and oxytocin antagonist metabolism in the plasma of pregnant humans and baboons. Gynecol Obstet Invest 2002; 54(1): 21-5.

 

46. TH An, CH Song, BC Choi, SC Pak, R Mehendale, G Flouret. Effect of an oxytocin antagonist on plasma oxytocin levels during noctural uterine contractions in the pregnant baboon. Gynecol Endocrinol 2002 Jun;16(3):173-8.

 

47. YH Bai, SC Pak, BC Choi, L Wilson Jr. Tocolytic effect of morphine via increased metabolic clearance of oxytocin in the baboon. Yonsei Med J 2002 43(5): 567-72.

 

48. HK Choi, BC Choi, SH Lee, JW Kim, KY Cha, KH Baek. Expression of angiogenesis- and apoptosis-related genes in chorionic villi derived from recurrent pregnancy loss patients. Mol Reprod Develop 2003; 66: 24-31.

 

49. TH An, CH Song, SC Pak, BC Choi, Lubomir Diveky, George Flouret. Development of a Radioreceptor Assay for Measuring an Oxytocin Antagonist in Blood. Gynecol Obstet Invest 2003; 56: 213-17.

 

50. JM Shin, JW Kim, BC Choi, SH Lee, KH Baek. Expression of Immunosupression-Related Genes in Fetal Chorionic Villi Derived from Recurrent Spontaneous Abortion patients. Kor J Fertil Seteril 2003; 30(3): 233~240.

 

51. JC Lee, SC Pak, YH Bai, CS Jin, BC Choi, et al., The Effect of Herbal Medicine on Nerve Growth Factor in Estradiol Valerate-induced Polycystic Ovaries in Rats. Am J Chinese Med 2003; 31(56): 885~895.

 

52. YH Bai, SC Pak, BC Choi, et al., Electro-Acupuncture Reveres Nerve Growth Factor Abundance in Experimental Polycystic Ovaries in the Rat. Gynecol Endocrinol 2004; 57:80-85.

 

53. J Ae Lee, SC Im, AR Lyu, BC Choi, CS Bae, et al., Effects of Red Ginseng Total Saponin on the Polycystic Ovaries in Rats. Kor J Biotechnol Bioeng 2004;19(6): 433~436.

 

54. SJ Han, TK Ahn, BC Choi, et al., A Case of PDT for Uterine Endometrial Carcinoma. J Kor Photodynamic Asso 2004; 1(1): 59~64.

 

55. J Ae Lee, KH Baek, JW Kim, BC Choi, et al., Trophoblast Apoptosis is increased in Women with Evidence of Th1 immunity. Fertil Steril 2005; 83(4):1047~1049.

 

56. Kim, Y.-S., Kim, M.-S., Lee, S.-H., Choi, B.-C., Lim, J.-M., Cha, K.-Y., and Baek, K.-H. Proteomic analysis of recurrent spontaneous abortion: Identification of an inadequately expressed set of proteins in human follicular fluid. Proteomics, 2006; 6: 3445-3454.

 

57. J Ae Lee, JS Oh, EK Choi, JW Kim, BC Choi, JH Cho et al. Differentially expressed genes implicated in unexplained recurrent spontaneous abortion. IJBCB 2007; 36: 2265~2277.

 

58. Kim JH, Yun JS, Sohng JK, Cha JM, Choi BC, Jeon HJ, Kim SH, Choi CH. Di(2-ethylhexyl)phthalate leached from medical PVC devices serves as a substrate and inhibitor for the P-glycoprotein. Environ toxicol pharmacol. 2007; 3(3): 272~278.

 

59. Chun KW, Song SJ, Choi BC, Lee HB, Lee SC, and Yoo KJ. Comparision of clinical efficacy between a single adeministration of long-acting GnRHa and daily admnistration of short acting GnRHa in in-vitro fertilization cycles. J. Korean Medical Science, 2008; 23(4):662-666.

 

60. H Park, BC Choi, SJ Song, DS Lee, JS Roh, S Chun. Luteinizing hormone-stimulated pituitary adenylate cyclase activating polypeptide system and its role in progesterone production in human luteinized granulosa cells. 2010; Endocrine Journal, 57(2), 127-134.

 

61. Li L, Yun JH, Lee JH, Song SJ, Choi BC and Baek KH. Association study of +45G15G(T/G) and +276(G/T) polymorphisms in the adiponectin gene in patients with polycystic ovarian syndrome. 2011; Int J Mol Med, 27, 283-287.

 

62. Park HJ, Kuk IS, Kim JH, Song SJ, Choi BC, Kim BK, and Song H. Characterization of Mouse Interferon-induced Transmembrane Protein-1 Gene Expression in the Mouse Uterus during the Estrous Cycle and Pregnancy(MIL-2) in the Mouse Uterus During the Estrus Cycle and Pregnancy. RD10086 Accepted 16 February 2011.

 

63. Kim MS, Gu BH, Song SJ, Choi BC, Cha DH, Farina A and Baek KH. ITI-H4, as an indicator in the serum of recurrent pregnancy loss(RPL) patients. Molecular BioSystems, 2011.

 

64. Kim JH,  Li L, Yun JH, Choi, BC and  Baek KH.  Association study between the -866G/A polymorphism in the promoter of uncoupling protein-2 gene and polycystic ovary syndrome. MOLECULAR MEDICINE REPORTS 00: 0-00, 2011.

 

 

 

 

 ABSTRACTS:

 

1. Hill JA, Choi BC, Ling X, Polgar K. The effect of progesterone on Th1 type immunity to trophoblast in women with recurrent pregnancy loss. J Soc Gynecol Invest 1997; 4(1)103:099.

 

2. Choi BC, Hill JA, Xiao L. IL-12 and IL-15 secretion in response to trophoblast in women with and without evidence of Th1 associated recurrent abortion and fertile controls. ASRM 1997;O-031.

 

3. Hill JA, Choi BC, Bermas BL. Proliferative responses to recall antigens are associated with pregnancy outcome in women with a history of recurrent spontaneous abortion and may be modified by immunosuppressive doses of progesterone. ASRM 1997;O-032.

 

4. Choi BC, Hill JA. Th1(IFN-γ), Th2(IL-10) and TGFβ1 secreation in response to trophoblast and progesterone in women with unexplained recurrent pregnancy loss and fertile controls. ASRM 1997;O-033.

 

5. Choi BC, Song JH, Yoo KJ, Song IO, Paik EC et al., When do losses of maternal lymphocytes response to trophoblast antigen or alloantigen occur in women with a history of recurrent miscarraige ? Kor J Fertil Sterl 1997; O-18.

 

6. Song JH, Choi BC, Koong MK, Yoo KJ, Song IO, JW Kim et al., Comparision of natural cycle and consequtive COH cycle in in Poor responders group. Kor J Fertil Sterl 1997; O-19.

 

7. Song JH, Choi BC, Yoo KJ, Song IO, HK Byun, Jun JH et al., Prediction and Clinical Evaluation of Ovarian Hyperstimulation Syndrome. Kor J Fertil Sterl 1997; P-1.

 

8. Choi BC, Yang KM, Paik EC et al., Chromosomal analysis of aborted conceptuses among anembryonic pregnancies and embryonic pregnancies: Are chromosomal abnormalities related to anembryonic pregnancy ? ASRM;1998:P-592.

 

9. Choi BC, Byun HK, Song JH et al., Is assisted ovulation time helpful in decreasing the incidence of chromosomal anomalies in recurrent spontaneous abortion ? ASRM;1998:P-153.

 

10. Song JH, Choi BC, Koong MK, Son IP, Yoo KJ, Song IO et al., Efficancy of clomiphene citrate stimulated cycle in poor responders in vitro fertilization. ASRM;1998:P-152.

 

11. Son IO, Choi BC, Song JH et al., Subsequent thawed embryo transfer following cryopreservation of all fresh embryos in women at risk of developing ovarian hyperstimulation syndrome(OHSS) may reduce the severity of the syndrome and improve the chance of pregnancy. ASRM;1998:P-329.

 

12. Lee HJ, Choi BC, Jun JH, Lim CG, et al., Factors influencing the outcome of ICSI with ejacualted, epididymal and testicular spermatozoa in 2000 consecutive cycles. ASRM;1998:P-342.

 

13. Choi BC, Byun HK, Lee JA et al., Th1 cytokine (IFN-γ) secretion pattern of peripheral blood mononuclear cells response to trophoblast antigen in women with unexplained recurrent spontaneous abortion and normal fertile controls. Kor J Fertil Steril 1998;O-1.

 

14. Jun JH, Choi BC, Lim CH, Song SJ et al., Outcome and statistical analysis of 2,000 consecutive ICSI treatment. Kor J Fertil Steril 1998;O-15.

 

15. Song IO, Song JH, Hong SJ, Yoo KJ, Paik EC, Choi BC, et al., Effica pregnancy rates of administration of prophylactic albumin or elective cryopreservation of all embryos for prevention of ovarian hyperstimulation syndrome in IVF-ET. Kor J Obst Gyn 1998. 41;6.

 

16. Kim SC, Kang SJ, Choi BC, Kimm KC. Ectopic telomerase reverse transcriptase (HTERT) expression of human cord blood T Lymphocyte. KSMBMB; 1998;B-5.

 

17. Whang CH, Choi BC, Byun HK, Moon IK et al., The effect of coelomic fluid from early trimester pregnancies to trophoblast cell proliferation in vitro culture system. 1999; ESHER:O

 

18. Choi BC, Lee JA, Kim JW et al., Immunolocalization of the apoptoic inhibiting protein (bcl-2) at the maternal-fetal interface in early pregnancies.1999; ESHER:O

 

19. Hong SJ, Choi BC, Song JH, Paik EC, et al. Frequency of chromosomal abnormalities in spontaneous abortions from IVF pregnancy: Does ART affect incidence of chromosomal abnormalities ? 1999; ESHER:O.

 

20. Song IO, Choi BC, Huh Y, Yoo KJ et al., Increased expression of endothelial nitric oxide synthetase in endometrium of infertile women with endometriosis or hydrosalpinx during the window of implantation. 1999; ESHER:O.

 

21. Choi BC, Kim SC, Lee HS, Bae KH, Anderson DJ, Hill JA, Kimm KC. Expression of telomerase activity in chorionic villi from missed abortion and undergoing surgical termination of first trimester pregnancy. 1999; ASRM:O.

 

22. Choi BC, Lee JA, Byun HK, Han HK, Koong MK, Son IP, Cho YY, Hill JA. Hydrosalpinx fluid inhibits trophoblast cell proliferation In vitro system: Implication for early implantation failure in women with hydrosalpinx fluid. 1999; ASRM:O.

23. KM Yang, BC Choi et al. The Incidence and Risk factors Associated with Ectopic pregnancy After IVF-ET. ASRM 2000: 56th Annual Meeting P-30.

 

24. JH Lee, BC Choi, SH Lee, CS Hwang, HM Chung, KY Cha, KH Baek. The analysis of genes in chorionic villi derived from recurrent spontaneous abortion. The 9th Federation Meeting of Korean Basic Medical Scientists 2001, P064

 

25. JW KIm, JA Lee, SC Shin, BC Choi, CH Song, SC Park. The expression of peptidyglycine α-amidating monooxygenase(PAM) in the placenta of pregnant women. ASRM 2001: 57th Annual Meeting.

 

26. KH Baek, JH Lee, BC Choi, SH Lee, HM Chung, KY Cha. The difference of Gene Expression Level at the Maternal-Fetal Interface between Normal and Recurrent Spontaneous Abortion patients. International Congress of Immunology 22-27, July 2001, Stockholm, Sweden.

 

27. KH Baek, HK Choi, BC Choi, JW Kim, KW Cha, et al. Angiogenesis is required for keeping normal pregnancy. 2001 American Society of Hematology, Annual Meeting, Orlando, Florida.

 

28. JW Kim, J Lee, BC Choi, KH Baek et al. Aberrant apoptosis in chorionic xilli is involved in recurrent miscarriage. O-169, 2002 Euopean Society of Human Reproduction and Embryology 18th Annual Meeting, Vienna.

 

29. KH Baek, BC Choi, HK Choi, JW Kim et al. Normal expression of angiogenesis-related gene is essential for the maintenance of normal pregnancy in humans. P-573, 2002 Euopean Society of Human Reproduction and Embryology 18th Annual Meeting, Vienna.

 

30. J Lee, JW Kim, BC Choi et al., Apoptosis in maternal-fetal interface may affect the fetal survival during early pregnancy. P-153, 58th ASRM, Seattle, Washington 2002.

 

31. J Lee, JW Kim, BC Choi et al., Trophoblast apoptosis is increased in women with evidence of Th-1 immunity. 59th ASRM, San Antonio, Texas, 2003.

 

32. YH Bai, SC Lim, CH Song, BC Choi, SC Pak et al. Electro-acupuncture reverse nerve growth factor abundance in experimental polycystic ovaries in the rat. The First World Congress on Chinese Medicine, Melbourne-Australia, 21-24 Nov 2003.

 

33. Proteomic analysis of polycystic ovary syndrome (PCOS): Identification of differentially expressed proteins. Yong-Soo Kim, Bo-Hyun Nam, Sook-Hwan Lee, Kwang-Yul Cha, Doo-Seok Choi, Ji-Ae Lee, Jeong-Wook Kim, Bum-Chae Choi and Kwang-Hyun Baek. 2004 The Korean Society of Fertility and Sterility.

 

34. Idenfication of a differentially expressed set of proteins in polycystic ovary syndrome (PCOS) patients. Yong-Soo Kim, Myung-Sun Kim, Sook-Hwan Lee, Kwang-Yul Cha, Ji-Ae Lee, Jeong-Wook Kim, Bum-Chae Choi and Kwang-Hyun Baek. 2005 KHUPO 5th International Proteomics Conference AOHUPO Workshop/Symposium.

 

35. Abnormal protein expression profiles in human follicular fluid from recurrent spontaneous abortion (RSA) patients. Myung-Sun Kim, Yong-Soo Kim, Sook-Hwan Lee, Kwang-Yul Cha, Ji-Ae Lee, Jeong-Wook Kim, Bum-Chae Choi and Kwang-Hyun Baek. 2005 KHUPO 5th International Proteomics Conference AOHUPO Workshop/Symposium.

 

36. Proteomic profiling of polycystic ovary syndrome (PCOS): Identification of highly expressed proteins. Yong-Soo Kim, Myung-Sun Kim, Sook-Hwan Lee, Kwang-Yul Cha, Doo-Seok Choi, Ji-Ae Lee, Jeong-Wook Kim, Bum-Chae Choi and Kwang-Hyun Baek. 2005 The Korean Society of Fertility and Sterility

 

37. Proteomic analysis of polycystic ovary syndrome (PCOS). Kwang-Hyun Baek, Yong-Soo Kim, Myung-Sun Kim, Sook-Hwan Lee, Kwang-Yul Cha, Doo-Seok Choi, Ji-Ae Lee, Jeong-Wook Kim and Bum-Chae Choi. 2005 13th World Congress in In Vitro Fertilization Assisted Reproduction & Genetics

 

38. Coagulation factors involved in recurrent pregnancy loss (RPL) Myung-Sun Kim , Yong-Soo Kim, Eung-Ji Lee, Brijesh S. Ajjappala, Sook-Hwan Lee, Bum-Chae Choi, Kwang-Yul Cha and Kwang-Hyun Baek. 2006 KHUPO 6th Annual International Proteomics Conference (Poster Award)

 

39. Protein biomarkers involved in polycystic ovary syndrome (PCOS). Yong-Soo Kim, Myung-Sun Kim , Brijesh S. Ajjappala, Min-Young Lee, Jung-Mi Park, In-Soo Han, and Kwang-Hyun Sook-Hwan Lee, Kwang-Yul Cha, Bum-Chae Choi, and Kwang-Hyun Baek. 2006 KHUPO 6th Annual International Proteomics Conference

 

40. Identification of coagulation factors involved in recurrent pregnancy loss. Kim MS, Kim YS, Lee EJ, Ajjappala BA, Lee SH, Choi BC, Cha KY, Beak KH 2006 The 5th Biannual Meeting of Pacific Rim Society for Fertility and Sterility.

 

41. Identification of over-expressed proteins by proteomic analysis using human follicular fluids derived from polycystic ovary syndrome (PCOS) patients. Myung-Sun Kim, Yong-Soo Kim, Jung-Mi Park,  Sook-Hwan Lee, Bum-Chae Choi, and Kwang-Hyun Baek. 2007 63th The American Society of Reproductive Medicine (Poster)

 

42. Proteomics application in human follicular fluid derived from polycystic ovary syndrome (PCOS) patients. Myung-Sun Kim, Yong-Soo Kim,  Bon Hee Gu,  Bum Chae Choi, Sook-Hwan Lee, and Kwang-Hyun Baek. 2007 7th KHUPO

 

43. Identification of inadequately expressed proteins in plasma of recurrent spontaneous abortion (RSA) patients. Min-Young Lee, Myung-Sun Kim, Bon Hee Gu,  Jong Ho Choi, Sang Jin Song, Bum Chae Choi and Kwang-Hyun Baek. 2008 HUPO 7th Annual World Congress (Amsterdam, Netherlands)

 

44. HB Lee, SJ Song, BC Choi, CS Bae. Modulation of Nerve Growth Factor (NGF) expression in a steroid-induced polycystic ovary rat treated with Korean Red Ginseng Extract 2010. 3rd Congress of the Asia Pacipic Initiative on Reproduction (ASPIRE), Bankok, Thailand, 9-11, April, 2010.

 

45. YS Chun, HY Chung, HB Lee, SJ Song and BC Choi, Apolipoprotein as a Novel Gene Associated with Polycystic Ovarian Syndrome. FertiLink2010, KYTO,Japan,2010.

Prize Paper Award